What distinguishes Primary Progressive MS from Relapsing-Remitting MS?

Primary Progressive Multiple Sclerosis (PPMS) is characterized by a gradual accumulation of disability from the onset of symptoms, without the distinct relapses and remissions that are typical of Relapsing-Remitting Multiple Sclerosis (RRMS). In PPMS, individuals experience a steady progression of neurological impairment over time, rather than experiencing intermittent periods of exacerbation (relapses) followed by recovery (remissions). This continuous decline in function is a defining factor that distinguishes it from RRMS, where patients have clear episodes of symptoms followed by periods of remission.

In contrast, other choices do not accurately portray the distinguishing features of PPMS. The notion of shorter episodes of remission is not applicable since PPMS does not feature remissions. Furthermore, it is not correct that PPMS solely occurs in older adults, as it can manifest in various age groups. Lastly, while individuals with any form of MS may require hospital visits, PPMS is not specifically characterized by frequent hospital visits more than other forms of MS. The defining element of PPMS remains its steady progression without the relapses characteristic of the relapsing-remitting form.