In which form of MS do patients experience progressive decline with occasional acute relapses?

The form of multiple sclerosis characterized by a progressive decline coupled with occasional acute relapses is known as Progressive-Relapsing Multiple Sclerosis (PRMS). This type of MS is distinguished by its combination of a steadily worsening neurological function from the onset of the disease, along with distinct periods of exacerbation or acute relapses. During these relapses, patients may experience new symptoms or a worsening of existing symptoms.

In PRMS, the progressive aspect means that there is a continuous accumulation of disability, and while relapses occur, there is no return to a baseline level of function, differentiating it from other forms of MS. This progression can lead to significant disability over time, and the relapses that occur can further complicate the patient's condition.

Other forms of MS have different patterns of progression. For instance, benign MS typically involves a mild course with few relapses and little or no disability, while Relapse Remitting Multiple Sclerosis (RRMS) features clearly defined relapses followed by periods of remission where the disease does not progress. Primary Progressive Multiple Sclerosis (PPMS), on the other hand, is marked by a gradual worsening of symptoms from the start without relapses. Thus, these characteristics distinctly identify PRMS as the correct choice in